Circumcision in HIV-infected men and its effect on HIV transmission to female partners in Rakai, Uganda: a randomised controlled trial
Study published in The Lancet, Volume 374, Issue 9685, Pages 229 - 237, 18 July 2009. doi:10.1016/S0140-6736(09)60998-3. The study assessed whether circumcision in HIV-infected men would reduce transmission of the virus to female sexual partners. Circumcision of HIV-infected men did not reduce HIV transmission to female partners over 24 months; longer-term effects could not be assessed. Condom use after male circumcision is essential for HIV prevention. The results indicate that there is a probability of 21.7% HIV infection rate for female partners of circumcised HIV infected men, compared to 13.4% HIV infection rate for female partners of HIV infected men. Women with circumcised partners had more than a 50% increase in the infection rate of women compared to women with un-circumcised partners.
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